Custom Synthesis

Selectoprobe is thrilled to offer our comprehensive Custom Synthesis services to meet your unique research and development needs. With Selectoprobe's Custom Synthesis, you can:

Customize: Specify the exact chemical structure, purity, and quantity of compounds you require, tailored precisely to your project requirements.

Quality Assurance: Rest assured knowing that our experienced chemists adhere to rigorous quality control measures to ensure the highest purity and consistency of synthesized compounds.

Confidentiality: Your intellectual property and proprietary information are safeguarded with our strict confidentiality agreements, ensuring complete discretion and confidentiality throughout the synthesis process.

Time and Cost Efficiency: Streamline your research and development efforts by outsourcing custom synthesis to Selectoprobe. Save valuable time and resources while accelerating your project timelines.

Whether you need novel molecules for drug discovery, specialized reagents for biochemical assays, or customized materials for advanced research applications, Selectoprobe's Custom Synthesis team is here to support you every step of the way.

Showing 13–16 of 16 results

  • Selectoprobeâ„¢ Europium Cryptate HTRF Labeling Reagent (Eu cryptate NHS ester)

    Catalog No.: SP-F-0148

    Description: The Europium cryptate labeling reagent is specifically designed for biomolecule labeling, enabling the rapid and efficient development of time-resolved fluorescence resonance energy transfer (TR-FRET) assays. It facilitates quick and easy labeling of peptides, proteins, and oligonucleotides.

    The N-hydroxysuccinimide (NHS)-activated Europium cryptate reacts with the primary amines on biomolecules, allowing for simplified and efficient conjugation.

    Compared to the other compounds, our Selectoprobeâ„¢ Cryptate Eu probes have extremely high stability, high emission yield and ability to selectively label biomolecules. Moreover, our Eu probes are insensitive to fluorescence quenching when conjugated to biological polymers such as antibodies.

    $500.00 – $68,571.00 Select options This product has multiple variants. The options may be chosen on the product page

  • Selectoprobeâ„¢ Horseradish Peroxidase (HRP) (High Purity, ≥250U/mg)

    Catalog No.: SP-F-0159

    Description: Selectoprobeâ„¢ Horseradish Peroxidase (HRP) is a high-purity horseradish peroxidase enzyme designed for optimal use in activity assays and antibody conjugation applications, including ELISA, Western blot, and immunohistochemistry.

    Key Features of Selectoprobeâ„¢ Horseradish Peroxidase:
    - Purified and Ready-to-Use: Lyophilized, salt-free powder form for easy dissolution and immediate use.
    - High Specific Activity: Typically greater than 300 units/mg (with lot-specific activity values provided).
    - Superior to AP: HRP (40kDa) is smaller and has a higher specific enzyme activity compared to alkaline phosphatase (AP; 140kDa) and beta-galactosidase (b-Gal).
    - Versatile Applications: Compatible with numerous substrate solutions and assay techniques, providing flexibility in assay design.

    Supplied as a lyophilized, salt-free powder, this HRP preparation is ideal for molecular biology and protein research applications, particularly as a reporter system in immunoassays and probe-based methods like ELISA, Western blotting, EMSA, and Southern blotting. Typically conjugated to secondary antibodies or streptavidin, HRP activity can be visualized using colorimetric or luminescent substrates.

    Horseradish peroxidase (HRP) interacts with hydrogen peroxide (Hâ‚‚Oâ‚‚) to form an [HRP-Hâ‚‚Oâ‚‚] complex, which can oxidize a broad range of hydrogen donors, including various substrates used in detection. These substrates include colorless, reduced chromogenic substrates (e.g., DAB, TMB, ABTS), chemiluminescent substrates (e.g., luminol), and fluorescent substrates (e.g., Amplex Red). Upon incubation with these substrates, HRP produces a colored, luminescent, or fluorescent product, allowing quantification through colorimetric, luminescent, or fluorimetric detection methods.

    HRP can be conjugated to antibodies using several techniques, such as glutaraldehyde, periodate oxidation, disulfide linkage, or amino- and thiol-directed cross-linkers. Compared to β-galactosidase and alkaline phosphatase, HRP’s smaller size and enhanced stability make it a preferred labeling enzyme for many applications.

    Storage: -20 °C; Minimize light exposure

     

    $978.80 – $5,990.00 Select options This product has multiple variants. The options may be chosen on the product page

  • Selectoprobeâ„¢ Mg-VI ionophore based ISE cocktail solution (for ion-selective electrodes, function tested)

    Catalog No: SP-I-0037

    for ion-selective electrodes, function tested

     

     

    $3,000.00 – $6,000.00 Select options This product has multiple variants. The options may be chosen on the product page

  • Selectoprobeâ„¢ polyHRP-Streptavidin Conjugate

    Catalog No.: SP-F-0158

    Description: Immunoassays (such as histochemistry, ELISAs and Western blotting) are important in clinical diagnosis and experimental protein analysis. These indirect analytical strategies primarily rely on the binding of an antigen by a specific antibody (primary antibody), followed by the detection of primary antibody by an enzyme or fluorescently labelled secondary antibody, allowing the semi-quantitative detection of a protein of interest. Histochemistry, ELISAs and Western blotting have been the common choices for protein validation studies for the past several decades. Technical advancements and modifications are continuously being developed to enhance the detection sensitivity of these procedures. Among them, streptavidin-containing poly-horseradish peroxidase (PolyHRP) based detection strategies have been shown to improve signals in a variety of immunoassays. The commercially available streptavidin and antibodies conjugated with many HRPs (PolyHRPs) have been widely used to enhance the detection sensitivity in immunoassays.

    Selectoprobeâ„¢ polyHRP-Streptavidin Conjugate is compatible with chromogenic, fluorogenic and chemiluminescent HRP substrates used in ELISA, Western blotting, immunohistochemistry (IHC) and nucleic acid hybridization assays. Due to the extremely high sensitivity of Selectoprobeâ„¢ polyHRP-Streptavidin Conjugate a blocking procedure may been needed to eliminate the interference caused by the endogenous biotinylated proteins.

    Storage: Refrigerated (2-8 °C); Minimize light exposure

     

    $590.00 – $5,600.00 Select options This product has multiple variants. The options may be chosen on the product page